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>   Home   >   Products   >   Primary Antibodies   >   Nogo B Receptor Rabbit mAb   

Nogo B Receptor Rabbit mAb

 
Catalog #
ABZ1921
Application
WB
Uniprot Id
Q96E22
Reactivity
Human, Mouse, Rat
Isotype
IgG
 
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  • Western blot analysis of Nogo B receptor in K562, 3T3, Hela lysates using Nogo B Receptor antibody.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ1921-100 2 weeks 100 µL $499.00
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ABZ1921-20 2 weeks 20 µL $149.00
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Product Overview

NameNogo B Receptor Rabbit mAb
Accession (Primary)Q96E22
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman, Mouse, Rat
Calculated MW
Calculated MW: 33 kDa; Observed MW: 33 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
With DHDDS, forms the dehydrodolichyl diphosphate synthase (DDS) complex, an essential component of the dolichol monophosphate (Dol-P) biosynthetic machinery. Both subunits contribute to enzymatic activity, i.e. condensation of multiple copies of isopentenyl pyrophosphate (IPP) to farnesyl pyrophosphate (FPP) to produce dehydrodolichyl diphosphate (Dedol-PP), a precursor of dolichol phosphate which is utilized as a sugar carrier in protein glycosylation in the endoplasmic reticulum (ER) (PubMed:21572394, PubMed:25066056, PubMed:28842490). Regulates the glycosylation and stability of nascent NPC2, thereby promoting trafficking of LDL-derived cholesterol. Acts as a specific receptor for the N-terminus of Nogo-B, a neural and cardiovascular regulator (PubMed:16835300).

Target Information: ( Q96E22 )

NameNUS1
Gene ID116150
Other Names
NgBR; MRD55; CDG1AA; C6orf68; TANGO14; MGC:7199
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