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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ1998-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ1998-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | MSRB3 Rabbit mAb |
|---|---|
| Accession (Primary) | Q8IXL7 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human, Mouse, Rat |
| Calculated MW | |
| Calculated MW: 21 kDa; Observed MW: 21 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| The methionine sulfoxide reductase B3 gene (MsrB3), a protein repair enzyme, has been implicated in large scale stereocilia bundle degeneration, as well as many other factors such as gestational age and tolerance to cold environments in plants. Although the exact process of pathogenesis is unknown, it seems to be related to apoptotic cell death. A study based on splicing morpholinos to down-regulate MsrB3 expression in zebrafish showed shorter, thinner, and more crowded cilia, as well as small, misplaced otoliths. Several stereocilia also underwent apoptosis. Injection with wild-type MsrB3 mRNA rescued auditory deficits, suggesting MsrB3 helps prevent apoptosis. | |
Target Information: ( Q8IXL7 ) | |
| Name | MSRB3 |
| Gene ID | 253827 |
| Other Names | |
| DFNB74; MSRB3 | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
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ADMEbio Team
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ADMEbio Team
