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>   Home   >   Products   >   Primary Antibodies   >   MMP12 Rabbit mAb   

MMP12 Rabbit mAb

 
Catalog #
ABZ4955
Application
WB, IP
Uniprot Id
P39900
Reactivity
Human
Isotype
IgG
 
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  • Western blot analysis of MMP12 in WI38 lysates using MMP12 antibody.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ4955-100 2 weeks 100 µL $499.00
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ABZ4955-20 2 weeks 20 µL $149.00
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Product Overview

NameMMP12 Rabbit mAb
Accession (Primary)P39900
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman
Calculated MW
Calculated MW: 54 kDa; Observed MW: 54,45,22 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000; IP-1:20-1:50
Purification
Affinity Chromatography
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
MMP-12 lacks a transmembrane domain and furin cleavage site. The zymogen for MMP-12 is about 54 kDa, and is quickly activated to the 45 kDa form, and this breaks down to cascade of active forms, ending with the common 22 kDa form.Stimulated macrophages produce MMP-12; it has also been found in osteosarcoma cells, synovial fibroblasts and lung fibroblasts.

Target Information: ( P39900 )

NameMMP12
Gene ID4321
Other Names
Macrophage metalloelastase; MME; 3.4.24.65; Macrophage elastase; ME; hME; Matrix metalloproteinase-12; MMP-12; MMP12; HME
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