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KD-Validated Anti-Beta-secretase 1 Rabbit Monoclonal Antibody

Rabbit monoclonal antibody

 
Catalog #
ABG1497
Application
WB, FC
Uniprot Id
P56817
Reactivity
Human, Mouse, Rat
Isotype
Rabbit IgG
 
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  • Western blotting analysis using anti-Beta-secretase 1 antibody (Cat#ABG1497). Total cell lysates (30 µg) from various cell lines were loaded and separated by SDS-PAGE. The blot was incubated with anti-Beta-secretase 1 antibody (Cat#ABG1497, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody respectively.
  • Western blotting analysis using anti-Beta-secretase 1 antibody (Cat#ABG1497). Beta-secretase 1 expression in wild type (WT) and Beta-secretase 1 shRNA knockdown (KD) HT-1080 cells with 30 µg of total cell lysates. β-Tubulin serves as a loading control. The blot was incubated with anti-Beta-secretase 1 antibody (Cat#ABG1497, 1:5,000) and HRP-conjugated goat anti-rabbit secondary antibody respectively.
  • Flow cytometric analysis of Beta-secretase 1 expression in C2C12 cells using Beta-secretase 1 antibody (Cat#ABG1497, 1:2,000). Green, isotype control; red, Beta-secretase 1.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABG1497-100 3 days 100 µL $499.00
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ABG1497-20 3 days 20 µL $149.00
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Product Overview

NameKD-Validated Anti-Beta-secretase 1 Rabbit Monoclonal Antibody
Accession (Primary)P56817
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeRabbit IgG
Clone Names23GB4865
Immunogen
A synthesized peptide derived from human BACE1
Species Reactivity
Reacts WithHuman, Mouse, Rat
Calculated MW
Predicted, 56 kD a , observed, 70 kDa
Storage Buffer
Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
Recommended Dilution
Western Blotting (WB): 1:1,000-1:5,000 Flow Cytometry (FCM):1:2,000

Target Information: ( P56817 )

Gene NameBACE1
Other Gene Names
BACE1; Beta-Secretase 1; BACE; Membrane-Associated Aspartic Protease; Beta-Site APP Cleaving Enzyme 1; Beta-Site APP-Cleaving Enzyme Aspartyl Protease; EC 3.4.23.46; Memapsin-2; Asp 2; ASP2; Beta-Site Amyloid Beta A4 Precursor Protein-Cleaving Enzyme; Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1; Transmembrane Aspartic Proteinase Asp2; Beta-Site APP-Cleaving Enzyme 1; APP Beta-Secretase; EC 3.4.23; KIAA1149; HSPC104
About Gene Symbol
BACE1 (Beta-Secretase 1) is a protease enzyme involved in receptor-mediated signaling. It is an important research target in cell signaling, drug discovery, and cancer research and is widely studied to elucidate cellular mechanisms and identify therapeutic targets.
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