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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABM0081-500 | 7 days | 500 µg | $550.00 |
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| ABM0081-1 | 7 days | 1 mg | $880.00 |
Product Overview | |
| Name | CD11b Antibody |
|---|---|
| Description | |
| CD11b, Mouse Anti-Human | |
| Immunogen | |
| Purified human PBL Monocytes. | |
| Synonyms | |
| Integrin alpha-M, Cell surface glycoprotein MAC-1 subunit alpha, CR-3 alpha chain, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, CD11b antigen, ITGAM, CR3A, MO1A, CD11B, MAC-1, MAC1A, MGC117044. | |
| Introduction | |
| Integrins are heterodimeric integral membrane proteins consisting of an ? chain and a ? chain. CD11b is an I-domain including ? integrin combines with the ? 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor also called MAC1. The ? M beta 2 integrin is crucial in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. | |
| Formulation | |
| 1mg/ml in PBS (after reconstitution). | |
| Solubility | |
| Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. | |
| Applications | |
| Blocking and staining antibody. For staining, use 10 µl/1,000,000 cells. Titer for blocking LPS binding should be determined by the investigator. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| hCD11b. | |
| Ig Subclass | |
| Mouse IgG1. | |
| Purification Method | |
| Ion exchange column. | |
| Storage Procedures | |
| Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. | |
| Available Conjugates | |
| This antibody is also available unconjugated and conjugated to FITC. For staining with biotin or FITC-conjugated antibody use 5-10 µl/1,000,000 cells. | |
| Precautions | |
| CD11b Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
