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CD21 Antibody, Biotin

CD21, Mouse Anti-Human, Biotin

 
Catalog #
ABM0094
 
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ABM0094-500 7 days 500 µg $550.00
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ABM0094-1 7 days 1 mg $880.00
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Product Overview

NameCD21 Antibody, Biotin
Description
CD21, Mouse Anti-Human, Biotin
Immunogen
Purified human B-Cells.
Synonyms
Complement receptor type 2, Cr2, Complement C3d receptor, Epstein-Barr virus receptor, EBV receptor, CD21 antigen, CR2, C3DR, CD21, SLEB9.
Introduction
CD21 is expressed strongly on mature B cells, follicular dentritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.
Formulation
1mg/ml in PBS (after reconstitution).
Solubility
Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Applications
Staining antibody. For staining, use 10 µl/1,000,000 cells.
Type
Mouse Anti Human Monoclonal.
Clone
hCD21.
Ig Subclass
Mouse IgG2a.
Purification Method
Protein-A.
Storage Procedures
Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.
Available Conjugates
This antibody is also available unconjugated and Biotin. For staining with biotin or FITC-conjugated antibody use 5-10 µl/10 6 cells.
Precautions
CD21 Antibody, Biotin is for research use only and not for use in diagnostic or therapeutic procedures.
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