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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABM0105-500 | 7 days | 500 µg | $550.00 |
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| ABM0105-1 | 7 days | 1 mg | $880.00 |
Product Overview | |
| Name | CD31 Biotin Antibody |
|---|---|
| Description | |
| CD31-Biotinylated, Mouse Anti Human | |
| Immunogen | |
| Enriched human platelets | |
| Synonyms | |
| Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA', CD31 antigen, PECAM1, CD31. | |
| Introduction | |
| CD31 is a glycoprotein expressed on endothelial cells, platelets, macrophages and Kupffer cells, granulocytes, T / NK cells, lymphocytes, megakaryocytes, fibroblasts, osteoclasts, neutrophils. In humans, the gene encoding CD31 is found on chromosome 17. CD31 is a cluster of differentiation molecule. It is also called PECAM-1 for platelet endothelial cell adhesion molecule. It plays a key role in removing aged neutrophils from the body. Both the neutrophil and the macrophage express CD31 on their membranes, and during the testing process, these CD31 molecules bind the two cells together. If the neutrophil is healthy, it will send a signal to the macrophage, and the CD31 molecules will detach. CD31 is also expressed in certain tumors, including epithelioid hemangioendothelioma, epithelioid sarcoma-like hemangioendothelioma, other vascular tumors, histiocytic malignancies, and plasmacytomas. It is rarely found in some sarcomas and carcinomas. | |
| Formulation | |
| 1mg/ml in PBS (after reconstitution). | |
| Solubility | |
| Reconstitute with H 2 0. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. | |
| Applications | |
| Flow cytometry, immunohistochemistry. For staining, use 10 µl/10 6 cells. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| hCD31 | |
| Ig Subclass | |
| mouse IgG1 | |
| Purification Method | |
| Protein A. | |
| Storage Procedures | |
| In lyophilized form, for long periods, store at 4°C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. | |
| Available Conjugates | |
| This antibody is also available conjugated to FITC and biotin. For flow cytometry use 5-10 µl/10 6 cells. | |
| Shipping Conditions | |
| Antibody is shipped lyophilized at ambient temperature. | |
| Note | |
| CD31 is expressed in high levels on endothelial cells and in lower levels on monocytes, granulocytes and platelets. | |
| Precautions | |
| CD31 Biotin Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
