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CD4 Antibody, FITC

Rat Anti-Mouse CD4, FITC

 
Catalog #
ABM0112
 
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ABM0112-500 7 days 500 µg $550.00
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ABM0112-1 7 days 1 mg $880.00
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Product Overview

NameCD4 Antibody, FITC
Description
Rat Anti-Mouse CD4, FITC
Immunogen
Purified human PBL CD4+ T cells.
Synonyms
gp55, HLA-2, L3 / T4, Ly-4, T cell antigen T4/LEU3, T4, sCD4, CD4mut.
Introduction
CD4 is a cell-surface glycoprotein found on the mature helper T cells and immature thymocytes, as well as on monocytes and macrophages. (Some cytotoxic T cells have CD4 protein as well.) Normally, about 65% of T cells in the blood are CD4+ (have CD4 protein protruding from their membrane). A mature T cell with either have CD4 or CD8, but not both. During one stage of development T cells develop CD4 and CD8 receptors, but they eventually are differentiated in the thymus and become more specialized.
Formulation
1mg/ml in PBS (after reconstitution).
Solubility
Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Applications
Blocking and staining antibody. Blocks blinding of HIV to CD4. For staining, use 10 ml/1,000,000 cells. Titer for blocking T cell activation should be determined by the investigator.
Type
Mouse Anti Human Monoclonal.
Clone
hCD4.
Ig Subclass
Mouse IgG2b.
Purification Method
Ion exchange column.
Storage Procedures
Lyophilized: store at 4oC. After reconstitution, if not intended for use within a month, aliquot and store at -20oC.
Available Conjugates
This antibody is also available conjugated to FITC.
Precautions
CD4 Antibody, FITC is for research use only and not for use in diagnostic or therapeutic procedures.
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