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>   Home   >   Products   >   Primary Antibodies   >   CD4 FITC Antibody   

CD4 FITC Antibody

CD4-FITC, Mouse Anti-Human

 
Catalog #
ABM0114
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABM0114-500 7 days 500 µg $550.00
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ABM0114-1 7 days 1 mg $880.00
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Product Overview

NameCD4 FITC Antibody
Description
CD4-FITC, Mouse Anti-Human
Synonyms
gp55, HLA-2, L3 / T4, Ly-4, T cell antigen T4/LEU3, T4, sCD4.
Introduction
CD4, a single chain transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is involved in recognition of antigen presented along with MHC class II by APCs. It serves as receptor for HIV. Antibody to CD4 recognizes T-helper cells required for recognition of class II antigens. It reacts with ~60% of peripheral blood E rosette-positive (E+) cells while showing negligible reactivity with E- cells, monocytes, granulocytes, EBV-transformed B cell lines, and mouse splenocytes.
Source
Escherichia Coli.
Physical Appearance
Sterile lyophilized powder.
Formulation
Each mg contains 1X PBS.
Stability
Store vial at -20oC to -80oC. When stored at the recommended temperature, this protein is stable for 12 months. Please avoid freeze-thaw cycles.
Purity
Greater than 90% as determined by SDS-PAGE.
Solubility
It is recommended to reconstitute the lyophilized CD-4 (125-202) in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
References
Title :Reduced Monomeric CD4 Is the Preferred Receptor for HIV. Publication : 10.1074/jbc.M110.190579 December 24, 2010 The Journal of Biological Chemistry, 285, 40793-40799. Link: http://www.jbc.org/content/285/52/40793.full#fn-1
Precautions
CD4 FITC Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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