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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABM0116-500 | 7 days | 500 µg | $550.00 |
Select product before adding to cart
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||
| ABM0116-1 | 7 days | 1 mg | $880.00 |
Product Overview | |
| Name | CD40 Antibody, Biotin |
|---|---|
| Description | |
| CD40, Mouse Anti-Human, Biotin | |
| Immunogen | |
| Activated Human B cells. | |
| Synonyms | |
| p50, Bp50, CDW40, MGC9013, TNFRSF5, CD40. | |
| Introduction | |
| CD40 is part of the TNF-receptor superfamily. CD40 is a necessary mediator for vast range of immune and inflammatory responses together with T cell-dependent immunoglobulin class switching, memory B cell growth, and germinal center formation. The transcription factor AKNA regulates the expression of CD40 and its ligand, which is vital for homotypic cell interactions. Adaptor protein TNFR2 interacts with CD40 and serves as a mediator of the signal transduction. The interaction of CD40 and its ligand is crucial for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is the receptor for TNFSF5/CD40L. | |
| Formulation | |
| 1mg/ml in PBS (after reconstitution). | |
| Solubility | |
| Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. | |
| Applications | |
| Staining antibody. For staining, use 10 µl/1,000,000 cells. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| hCD40. | |
| Ig Subclass | |
| Mouse IgG1. | |
| Purification Method | |
| Protein-A. | |
| Storage Procedures | |
| Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. | |
| Available Conjugates | |
| This antibody is also available unconjugated and conjugated to Biotin. For staining with biotin or FITC-conjugated antibody use 5-10 µl/10 6 cells. | |
| Precautions | |
| CD40 Antibody, Biotin is for research use only and not for use in diagnostic or therapeutic procedures. | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
