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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABM0139-500 | 7 days | 500 µg | $550.00 |
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| ABM0139-1 | 7 days | 1 mg | $880.00 |
Product Overview | |
| Name | CD8 Antibody |
|---|---|
| Description | |
| CD8, Rat Anti-Mouse | |
| Immunogen | |
| Purified human PBL CD8+ T cells. | |
| Synonyms | |
| CD8, MAL, p32. | |
| Introduction | |
| CD8 is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 acts as a co-receptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional CD8 is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. CD8 identifies cytotoxic/suppressor t-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of t-cell mediated killing. CD8 alpha chains binds to class-I MHC molecules alpha-3 domains. | |
| Formulation | |
| 1mg/ml in PBS (after reconstitution). | |
| Solubility | |
| Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. | |
| Applications | |
| Staining antibody, weakly cytotoxic. For staining, use 10 µl/1,000,000 cells. Titer for cytotoxicity should be determined by the investigator. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| hCD8. | |
| Ig Subclass | |
| Mouse IgG2a. | |
| Purification Method | |
| Ion exchange column. | |
| Storage Procedures | |
| Lyophilized: store at 4C. After reconstitution, if not intended for use within a month, aliquot and store at -20C. | |
| Available Conjugates | |
| This antibody is also available conjugated to FITC. | |
| Precautions | |
| CD8 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
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ADMEbio Team
