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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABM0147-500 | 7 days | 500 µg | $550.00 |
Select product before adding to cart
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| ABM0147-1 | 7 days | 1 mg | $880.00 |
Product Overview | |
| Name | CD86 Antibody, Biotin |
|---|---|
| Description | |
| CD86, Rat Anti-Mouse, Biotinylated | |
| Immunogen | |
| Purified mouse LPS-activated B cells. | |
| Synonyms | |
| B70, B7-2, LAB72, CD28LG2, FUN-1, BU63. | |
| Introduction | |
| CD86 type I membrane protein is a member of the immunoglobulin superfamily which is expressed by antigen-presenting cells, and acts as the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. CD86 binding with CD28 protein is a co-stimulatory signal for initiation of the T-cell. CD86 binding with CTLA-4 negatively regulates T-cell activation and diminishes the immune response. | |
| Formulation | |
| 1mg/ml in PBS (after reconstitution). | |
| Solubility | |
| Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. | |
| Applications | |
| Blocking and staining antibody. For staining, use 10 µl/1,000,000 cells. Titer for blocking T cell activation should be determined by the investigator. | |
| Type | |
| Rat Anti Mouse Monoclonal. | |
| Clone | |
| mB7-2. | |
| Ig Subclass | |
| Rat IgG2a. | |
| Purification Method | |
| Protein-A. | |
| Storage Procedures | |
| Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C. | |
| Available Conjugates | |
| This antibody is only available non-conjugated and conjugated to Biotin. | |
| Precautions | |
| CD86 Antibody, Biotin is for research use only and not for use in diagnostic or therapeutic procedures. | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
