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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABM0170-5 | 7 days | 5 µg | $120.00 |
Select product before adding to cart
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||
| ABM0170-20 | 7 days | 20 µg | $290.00 | |||
| ABM0170-100 | 7 days | 100 µg | $720.00 |
Product Overview | |
| Name | C-Myc (410-419aa) Antibody |
|---|---|
| Description | |
| c-Myc (410-419aa), Mouse Anti Human | |
| Immunogen | |
| synthetic peptides. | |
| Synonyms | |
| MYC, CMYC, C-MYS, V-MYC, P64. | |
| Introduction | |
| c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. | |
| Formulation | |
| 1mg/ml in PBS (after reconstitution). | |
| Solubility | |
| Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use. | |
| Type | |
| Mouse Anti Human Monoclonal. | |
| Clone | |
| NYRhc-myc. | |
| Ig Subclass | |
| mouse IgG1. | |
| Purification Method | |
| Protein A. | |
| Storage Procedures | |
| Antibody is shipped lyophilized at ambient temperature. | |
| Titer | |
| By Western blot 1:2,000 dilution will yield a strong band in WB. | |
| Note | |
| This antibody was produced in BALB/c mice. | |
| Precautions | |
| C-Myc (410-419aa) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
