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CRADD Antibody

Caspase and RIP Adapter with Death Domain, Mouse Anti Human

 
Catalog #
ABM0183
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABM0183-5 7 days 5 µg $120.00
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ABM0183-20 7 days 20 µg $290.00
ABM0183-100 7 days 100 µg $720.00
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Product Overview

NameCRADD Antibody
Description
Caspase and RIP Adapter with Death Domain, Mouse Anti Human
Synonyms
RAIDD, MGC9163, CRADD, Death domain-containing protein CRADD, Caspase and RIP adapter with death domain, RIP-associated protein with a death domain, CASP2 and RIPK1 domain containing adaptor with death domain.
Introduction
CRADD is a 22kDa, widely-expressed cytosolic adaptor/signaling protein that induces cell apoptosis/cell death in numerous tissues. CRADD is a death domain (CARD) that recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes TNFR1A, RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
The CRADD protein solution (1mg/ml) contains 20mM Tris-HCl pH-8 and 20% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 95.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MEARDKQVLR SLRLELGAEV LVEGLVLQYL YQEGILTENH IQEINAQTTG LRKTMLMLDI LPSRGPKAFD TFLDSLQEFP WVREKLKKAR EEAMTDLPAG DRLTGIPSHI LNSSPSDRQI NQLAQRLGPE WEPMVLSLGL SQTDIYRCKA NHPHNVQSQV VEAFIRWRQR FGKQATFQSL HNGLRAVEVD PSLLLHMLE.
Precautions
CRADD Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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