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FKBP6 Antibody

FK506 Binding Protein 6, Mouse Anti Human

 
Catalog #
ABM0255
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABM0255-5 7 days 5 µg $120.00
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ABM0255-20 7 days 20 µg $290.00
ABM0255-100 7 days 100 µg $720.00
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Product Overview

NameFKBP6 Antibody
Description
FK506 Binding Protein 6, Mouse Anti Human
Synonyms
FKBP36, EC 5.2.1.8, FKBP-6, PPIase, MGC87179, FK506-binding protein 6, Rotamase.
Introduction
FKBP6 is part of the immunophilin protein family, and is involved in immunoregulation and basic cellular functions involving protein folding and trafficking. FKBP6 is widely expressed in all tissues, FKBP6 is present at utmost levels in testis, liver, kidney, skeletal muscle and heart. Deletion of FKBP6 contributes to hypercalcemia and growth delay in Williams-Beuren syndrome.
Physical Appearance
Sterile filtered colorless solution.
Formulation
0.5mg/ml solution containing 20mM Trsi HCL pH-8, 1mM DTT, 1mM EDTA, 0.2M NaCl & 40% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 95% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MGGSALNQGV LEGDDAPGQS LYERLSQRML DISGDRGVLK DVIREGAGDL VAPDASVLVK YSGYLEHMDR PFDSNYFRKT PRLMKLGEDI TLWGMELGLL SMRRGELARF LFKPNYAYGT LGCPPLIPPN TTVLFEIELL DFLDCAESDK FCALSAEQQD QFPLQKVLKV AATEREFGNY LFRQNRFYDA KVRYKRALLL LRRRSAPPEE QHLVEAAKLP VLLNLSFTYL KLDRPTIALC YGEQALIIDQ KNAKALFRCG QACLLLTEYQ KARDFLVRAQ KEQPFNHDIN NELKKLASCY RDYVDKEKEM WHRMFAPCGD GSTAGES.
Biological Activity
Specific activity is > 190 nmoles/min/mg, and is defined as the amount of enzyme that cleaves 1umole of suc-AAFP-pNA per minute at 25C in Tris-Hcl pH8.0 using chymotrypsin.
Precautions
FKBP6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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