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IFN g Antibody

Interferon-gamma, Mouse Anti-Human

 
Catalog #
ABM0360
 
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ABM0360-500 7 days 500 µg $550.00
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ABM0360-1 7 days 1 mg $880.00
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Product Overview

NameIFN g Antibody
Description
Interferon-gamma, Mouse Anti-Human
Synonyms
Interferon gamma, IFN-gamma, IFNG.
Introduction
IFN-gamma produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4 and 5% trehalose.
Stability
Lyophilized Interferon-gamma although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFN-gamma should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Amino acid sequence
QAAFFKEIEN LKEYFNASNP DVGDGGPLFL DILKNWKEDS DKKIIQSQIV SFYFKLFENL KDNQVIQKSM DTIKEDLFVK FFNSSTSKLE DFQKLIQIPV NDLKVQRKAI SELIKVMNDL SPKANLRKRK RSQNPFRGRR ALQ.
Biological Activity
The ED 50 as determined by an anti-viral assay using human HeLa cells infected with encephalomyocarditis (EMC) virus is less than 10.0 ng/ml, corresponding to a specific activity of > 1.0 × 10 5 IU/mg.
Solubility
It is recommended to reconstitute the lyophilized Interferon-gamma in sterile 18M-cm H 2 O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Precautions
IFN g Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

References

1.Title: Activation of human NK cells by plasmacytoid dendritic cells and its modulation by CD4+T helper cells and CD4+CD25hiT regulatory cells Publications: Eur. J. Immunol. 2005. 35: 2452–2458 Link: IFN g Antibody prospec publication

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