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IgA Sec antibody

IgA Secretory Component, Mouse Anti-Human

 
Catalog #
ABM0365
 
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ABM0365-500 7 days 500 µg $550.00
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ABM0365-1 7 days 1 mg $880.00
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Product Overview

NameIgA Sec antibody
Description
IgA Secretory Component, Mouse Anti-Human
Immunogen
r.Human Growth Hormone
Synonyms
Somatomedin C, IGF-I, IGFI, IGF1, IGF-IA, Mechano growth factor, MGF.
Introduction
The somatomedins, or insulin-like growth factors (IGFs), comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone (GH; MIM 139250). Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed 'sulfation factor,' which later became known as 'somatomedin' (Daughaday et al., 1972). Three main somatomedins have been characterized: somatomedin C (IGF1), somatomedin A (IGF2; MIM 147470), and somatomedin B (MIM 193190) (Rotwein, 1986; Rosenfeld, 2003).
Formulation
1mg/ml in PBS (after reconstitution).
Solubility
Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Applications
Direct ELISA, Western Blot, Immuneprecipitation.
Type
Mouse Anti Human Monoclonal.
Clone
NYRhIGF1
Ig Subclass
Mouse IgM
Purification Method
Boric acid precipitation
Storage Procedures
Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.
Titer
By direct ELISA, 1:10,000 dilution will yield 0.5 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories).
Precautions
IgA Sec antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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