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IL 4 Antibody

Interleukin-4, Rat Anti-Mouse

 
Catalog #
ABM0384
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABM0384-500 7 days 500 µg $550.00
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ABM0384-1 7 days 1 mg $880.00
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Product Overview

NameIL 4 Antibody
Description
Interleukin-4, Rat Anti-Mouse
Immunogen
r.Human IL-4.
Synonyms
BCGF, BCDF, B cell stimulating factor, BSF-1, Lymphocyte stimulatory factor 1, IL-4, MGC79402, Binetrakin, Pitrakinra.
Introduction
IL4 is a pleiotropic cytokine produced by activated T cells. IL4 is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. IL4, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Formulation
1mg/ml in PBS (after reconstitution).
Solubility
Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Type
Mouse Anti Human Monoclonal.
Clone
NYRhIL4.
Ig Subclass
Mouse IgG2a Purification MethodIon exchange.
Storage Procedures
In lyophilized form, for long periods, store at 4oC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20oC.
Shipping Conditions
Antibody is shipped lyophilized at ambient temperature.
Titer
In direct ELISA, using alkaline phosphatase goat anti-mouse Ig (Jackson Laboratories) 1:10,000 dilution will give 0.3 O.D.
Precautions
IL 4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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