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LYVE1 Antibody

Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1, Mouse Anti Human

 
Catalog #
ABM0452
 
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ABM0452-5 7 days 5 µg $120.00
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ABM0452-20 7 days 20 µg $290.00
ABM0452-100 7 days 100 µg $720.00
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Product Overview

NameLYVE1 Antibody
Description
Lymphatic Vessel Endothelial Hyaluronic Acid Receptor 1, Mouse Anti Human
Synonyms
Lymphatic vessel endothelial hyaluronic acid receptor 1 precursor, LYVE-1, Cell surface retention sequence-binding protein 1, CRSBP-1, Hyaluronic acid receptor, Extracellular link domain-containing protein 1.
Introduction
LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41% similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.
Source
Insect Cells.
Physical Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
LYVE1 was lyophilized from a concentrated (1 mg/ml) sterile solution containing no additives.
Stability
Lyophilized sLYVE-1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution sLYVE-1 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Purity
Greater than 95.0% as determined by(a)Analysis by RP-HPLC. (b)Analysis by SDS-PAGE.
Solubility
It is recommended to reconstitute the lyophilized LYVE1 in sterile water not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Precautions
LYVE1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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