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Myc (PMYCSHG) Antibody

Myc, Mouse Antibody

 
Catalog #
ABM0485
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABM0485-100 7 days 100 µg $310.00
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ABM0485-0.2 7 days 0.2 mg $580.00
ABM0485-0.5 7 days 0.5 mg $1,040.00
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Product Overview

NameMyc (PMYCSHG) Antibody
Description
Myc, Mouse Antibody
Synonyms
MYC, CMYC, C-MYS, V-MYC, P64.
Introduction
c-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of c-Myc have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Formulation
Serum with 0.02% sodium azide.
Applications
Western Blot, Immunoprecipitation.
Type
Polyclonal Rabbit Antibody.
Clone
PPMYCSHG.
Titer
Western Blotting: 1:500.
Precautions
Myc (PMYCSHG) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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