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PAIP2 Antibody

Polyadenylate-Binding Protein-Interacting Protein 2, Mouse Anti Human

 
Catalog #
ABM0527
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABM0527-5 7 days 5 µg $120.00
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ABM0527-20 7 days 20 µg $290.00
ABM0527-100 7 days 100 µg $720.00
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Product Overview

NamePAIP2 Antibody
Description
Polyadenylate-Binding Protein-Interacting Protein 2, Mouse Anti Human
Synonyms
Poly(A) Binding Protein Interacting Protein 2, PABP- interacting protein 2, HSPC218, PAIP-2, PAIP2A, Polyadenylate-binding protein-interacting protein 2, PAIP2, MGC72018.
Introduction
PAIP2 has a role as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. PAIP2 inhibitory activity on translation is mediated through its action on PABPC1. PAIP2 displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. PAIP2 association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
Source
Escherichia Coli.
Physical Appearance
Sterile filtered colorless solution.
Formulation
The PAIP2 protein solution contains 20mM Tris-HCl, pH-8, 1mM DTT & 10% Glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MKDPSRSSTS PSIINEDVII NGHSHEDDNP FAEYMWMENE EEFNRQIEEE LWEEEFIERC FQEMLEEEEE HEWFIPARDL PQTMDQIQDQ FNDLVISDGS SLEDLVVKSN LNPNAKEFVP GVKYGNI.
Precautions
PAIP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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