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SARS CoV-2 IgG S1

Recombinant Anti Human SARS CoV-2 IgG Spike S1, Monoclonal

 
Catalog #
ABM0606
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABM0606-50 7 days 50 µg $1,800.00
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ABM0606-150 7 days 150 µg $4,500.00
ABM0606-250 7 days 250 µg $4,800.00
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Product Overview

NameSARS CoV-2 IgG S1
Description
Recombinant Anti Human SARS CoV-2 IgG Spike S1, Monoclonal
Immunogen
The native monoclonal antibody was generated by sequencing peripheral blood lymphocytes of a patient exposed to the SARS-CoV. Mouse Anti Human SARS CoV-2 IgM Kappa Spike S1 Reformatted using the variable domain sequences of the original Human IgG1 format.
Introduction
SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies.It has recently been shown that SARS is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics.
Source
HEK293 Cells
Physical Appearance
Sterile Filtered liquid formulation.
Formulation
1mg/ml in PBS and 0.02% Proclin 300.
Stability
Store at 4°C, stable for 2 weeks. For long-term storage, store at -20°C.
Applications
ELISA
Type
Mouse antibody Monoclonal.
Purification Method
Affinity purified via recombinant lectin column.
Precautions
SARS CoV-2 IgG S1 is for research use only and not for use in diagnostic or therapeutic procedures.
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