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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABM0613-5 | 7 days | 5 µg | $350.00 |
Select product before adding to cart
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| ABM0613-10 | 7 days | 10 µg | $500.00 | |||
| ABM0613-100 | 7 days | 100 µg | $2,400.00 |
Product Overview | |
| Name | SARS Nucleocapsid Monoclonal |
|---|---|
| Description | |
| SARS-Nucleocapsid, Monoclonal Antibody | |
| Accession (Primary) | NP_828858.1 |
| Immunogen | |
| The antibody was developed by immunizing rabbits with synthetic peptides corresponding to amino a.a. 399-411 of putative SARS nucleocapsid (Genbank accession no. YP_009724397.2). | |
| Introduction | |
| SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies. It has recently been shown that SARS is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics. | |
| Formulation | |
| 1mg/ml in PBS and 0.02% sodium azide. | |
| Stability | |
| Store at 4°C, stable for 2 weeks. For long-term storage, store at -20°C. | |
| Applications | |
| Western Blot 1:100-1:2000, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1:10-1:500 | |
| Type | |
| Polyclonal Rabbit Antibody. | |
| Precautions | |
| SARS Nucleocapsid Monoclonal is for research use only and not for use in diagnostic or therapeutic procedures. | |
Target Information: ( NP_828858.1 ) | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
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Thank you,
ADMEbio Team
