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TNNI1 Paired Antibody

Mouse Anti Human Troponin I Type 1 Paired

 
Catalog #
ABM0661
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABM0661-5 7 days 5 µg $120.00
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ABM0661-20 7 days 20 µg $290.00
ABM0661-100 7 days 100 µg $720.00
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Product Overview

NameTNNI1 Paired Antibody
Description
Mouse Anti Human Troponin I Type 1 Paired
Synonyms
Troponin I fast skeletal muscle, Troponin I fast-twitch isoform, TNNI2, DA2B, FSSV, fsTnI, AMCD2B.
Introduction
TNNI2 is a fast-twitch skeletal muscle protein, belongs to the troponin I gene family, and is part of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, together with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. TNNI2 is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. Other than muscle tissues, TNNI2 is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a coactivator of estrogen receptor-related receptor alpha. Furthermore, TNNI2 suppresses tumor growth in human ovarian carcinoma. Mutations in the TNNI2 gene cause myopathy and distal arthrogryposis type 2B.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colourless liquid formualtion.
Formulation
The protein solution contains 20mM Tris-HCl, 500mM NaCl and 10mM b-ME, pH 7.5.
Stability
TNNI2 Human although stable at 10°C for 7 days, should be stored below -18°C. Please prevent freeze-thaw cycles.
Purity
Greater than 97.0% as determined by SDS-PAGE.
Precautions
TNNI1 Paired Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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