| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABM0661-5 | 7 days | 5 µg | $120.00 |
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| ABM0661-20 | 7 days | 20 µg | $290.00 | |||
| ABM0661-100 | 7 days | 100 µg | $720.00 |
Product Overview | |
| Name | TNNI1 Paired Antibody |
|---|---|
| Description | |
| Mouse Anti Human Troponin I Type 1 Paired | |
| Synonyms | |
| Troponin I fast skeletal muscle, Troponin I fast-twitch isoform, TNNI2, DA2B, FSSV, fsTnI, AMCD2B. | |
| Introduction | |
| TNNI2 is a fast-twitch skeletal muscle protein, belongs to the troponin I gene family, and is part of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, together with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. TNNI2 is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. Other than muscle tissues, TNNI2 is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a coactivator of estrogen receptor-related receptor alpha. Furthermore, TNNI2 suppresses tumor growth in human ovarian carcinoma. Mutations in the TNNI2 gene cause myopathy and distal arthrogryposis type 2B. | |
| Source | |
| Escherichia Coli. | |
| Physical Appearance | |
| Sterile Filtered colourless liquid formualtion. | |
| Formulation | |
| The protein solution contains 20mM Tris-HCl, 500mM NaCl and 10mM b-ME, pH 7.5. | |
| Stability | |
| TNNI2 Human although stable at 10°C for 7 days, should be stored below -18°C. Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 97.0% as determined by SDS-PAGE. | |
| Precautions | |
| TNNI1 Paired Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team