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TOLLIP Antibody

Toll-interacting protein, Mouse Anti Human

 
Catalog #
ABM0663
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABM0663-5 7 days 5 µg $120.00
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ABM0663-20 7 days 20 µg $290.00
ABM0663-100 7 days 100 µg $720.00
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Product Overview

NameTOLLIP Antibody
Description
Toll-interacting protein, Mouse Anti Human
Synonyms
Toll-interacting protein, TOLLIP, IL-1RAcPIP.
Introduction
Toll interacting protein (TOLLIP) is an inhibitory adaptor protein within Toll-like receptors. The TLR pathway is a part of the innate immune system which recognizes structurally conserved molecular patterns of microbial pathogens, initiating an inflammatory immune response. Negative regulation of TLR signaling by TOLLIP might restrict the production of proinflammatory mediators during inflammation and infection. Furthermore, TOLLIP forms a complex with Tom1 to regulate endosomal transferring of ubiquitinated proteins.
Source
Escherichia Coli.
Physical Appearance
Sterile Filtered colorless solution.
Formulation
TOLLIP protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 40% glycerol, 0.2M NaCl and 2mM DTT.
Stability
TOLLIP Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.
Purity
Greater than 85.0% as determined by SDS-PAGE.
Amino acid sequence
MGSSHHHHHH SSGLVPRGSH MATTVSTQRG PVYIGELPQD FLRITPTQQQ RQVQLDAQAA QQLQYGGAVG TVGRLNITVV QAKLAKNYGM TRMDPYCRLR LGYAVYETPT AHNGAKNPRW NKVIHCTVPP GVDSFYLEIF DERAFSMDDR IAWTHITIPE SLRQGKVEDK WYSLSGRQGD DKEGMINLVM SYALLPAAMV MPPQPVVLMP TVYQQGVGYV PITGMPAVCS PGMVPVALPP AAVNAQPRCS EEDLKAIQDM FPNMDQEVIR SVLEAQRGNK DAAINSLLQM GEEP.
Precautions
TOLLIP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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