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IGLL1 Antibody

Immunoglobulin Lambda-Like Polypeptide 1, Mouse Anti Human

 
Catalog #
ABM0714
 
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ABM0714-5 7 days 5 µg $100.00
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ABM0714-20 7 days 20 µg $260.00
ABM0714-100 7 days 100 µg $720.00
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Product Overview

NameIGLL1 Antibody
Description
Immunoglobulin Lambda-Like Polypeptide 1, Mouse Anti Human
Immunogen
r.Murine IL-10.
Synonyms
B-TCGF, CSIF, TGIF, IL-10, IL10A, MGC126450, MGC126451, Cytokine synthesis inhibitory factor.
Introduction
IL10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
Formulation
1mg/ml in PBS (after reconstitution)
Solubility
Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Type
Rat Anti Mouse Monoclonal.
Clone
MI10-L2
Ig Subclass
Rat IgM.
Purification Method
Boric Acid precipitation/ S-Sepharose.
Storage Procedures
In lyophilized form, for long periods, store at 4ºC in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20ºC.
Shipping Conditions
Antibody is shipped lyophilized at ambient temperature.
Titer
By direct ELISA, 1:1000, By western Blot, 1:2000.
Specificity
Mouse IL-10.
Cross reactivity
Does not cross-react with human IL-10.
Precautions
IGLL1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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