| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABM0716-5 | 7 days | 5 µg | $100.00 |
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| ABM0716-20 | 7 days | 20 µg | $260.00 | |||
| ABM0716-100 | 7 days | 100 µg | $720.00 |
Product Overview | |
| Name | LAIR1 Antibody |
|---|---|
| Description | |
| Leukocyte-Associated Ig-Like Receptor 1, Mouse Anti Human | |
| Synonyms | |
| Left-right determination factor 1, Left-right determination factor B, Protein lefty-1, Protein lefty-B, LEFTY1, LEFTB, LEFTYB. | |
| Introduction | |
| Left-Right Determination Factor 1 (LEFTY1) belongs to the TGF-beta family of proteins. LEFTY1 is required for left-right axis determination as a regulator of LEFTY2 and NODAL. An analogous secreted protein in mouse has a role in left-right asymmetry determination of organ systems during development. The LEFTY1 gene is closely linked to both a related family member and a related pseudogene. | |
| Source | |
| HEK. | |
| Physical Appearance | |
| Sterile Filtered White lyophilized (freeze-dried) powder. | |
| Formulation | |
| The LEFTY1 was lyophilized from 1mg/ml in 1xPBS. | |
| Stability | |
| Lyophilized LEFTY1 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution LEFTY1 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. | |
| Purity | |
| Greater than 90% as obsereved by SDS-PAGE. | |
| Biological Activity | |
| The specific activity was determined by dose dependent ability to inhibit BMP-4 (6.5 ng/mL) induction of alkaline phosphatase production in the MC-3T3-E1 cell line (Mouse chondrogenic cell line) and is typically 10-40ng/ml. | |
| Solubility | |
| It is recommended to reconstitute the lyophilized LEFTY1 in sterile water not less than 100 µg/ml, which can then be further diluted to other aqueous solutions. | |
| Precautions | |
| LAIR1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. | |
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ADMEbio Team
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ADMEbio Team