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NCSTN Antibody

Nicastrin, Mouse Anti Human

 
Catalog #
ABM0720
 
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ABM0720-5 7 days 5 µg $100.00
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ABM0720-20 7 days 20 µg $260.00
ABM0720-100 7 days 100 µg $720.00
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Product Overview

NameNCSTN Antibody
Description
Nicastrin, Mouse Anti Human
Immunogen
Anti-human NDE1 mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human NDE1 amino acids 1-335 purified from E. coli
Synonyms
Nuclear distribution protein nudE homolog 1, NudE, NDE1, NUDE, LIS4, NUDE1, HOM-TES-87.
Introduction
NDE1 is a cytoplasmic protein which is a member of the nudE protein family. Phosphorylated during mitosis, NDE1 is critical for the formation and function of the mitotic spindle in M phase and functions to regulate the Dynein-mediated transport of kinetochore proteins, as well as centrosome duplication during interphase. NDE1 is believed to interact with NDEL1, LIS1 and Dynein IC1/2, cytosolic in a signaling pathway which regulates the formation of neurons and is fundamental to the development of the cerebral cortex.
Formulation
1mg/ml containing PBS, pH-7.4, & 0.1% Sodium Azide.
Applications
NDE1 antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500.
Type
Mouse Anti Human Monoclonal.
Clone
P1F7AT.
Ig Subclass
Mouse IgG 1 heavy chain and ? light chain.
Purification Method
NDE1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Storage Procedures
For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.
Stability / Shelf Life
12 months at -20°C. 1 month at 4°C.
Precautions
NCSTN Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
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