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SARS Nucleocapsid Polyclonal

SARS-Nucleocapsid protein, Polyclonal Antibody

 
Catalog #
ABP0027
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABP0027-5 7 days 5 µg $350.00
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ABP0027-10 7 days 10 µg $500.00
ABP0027-100 7 days 100 µg $2,880.00
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Product Overview

NameSARS Nucleocapsid Polyclonal
Description
SARS-Nucleocapsid protein, Polyclonal Antibody
Immunogen
Recombinant protein fragment 1-49 a.a. of the SARS nucleoprotein.
Introduction
SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies.It has recently been shown that SARS is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics.
Physical Appearance
Sterile Filtered liquid formulation.
Formulation
1mg/ml in PBS and 0.09% NaN3.
Stability
Store at 4°C, stable for 2 weeks. For long-term storage, store at -20°C.
Purity
Greater than 90% as determined by SDS-PAGE gel.
Applications
ELISA.
Type
Mouse antibody Monoclonal.
Clone
PT3851
Purification Method
Protein A affinity purified.
Precautions
SARS Nucleocapsid Polyclonal is for research use only and not for use in diagnostic or therapeutic procedures.
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