| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ1070-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ1070-20 | 2 weeks | 20 µL | $149.00 | |||
| ABZ1070-50 | 2 weeks | 50 µL | $325.00 |
Product Overview | |
| Name | [KO] YAP Mouse mAb |
|---|---|
| Accession (Primary) | P46937 |
| Host Species | Mouse |
| Isotype | IgG1 |
| Immunogen | |
| Purified recombinant human YAP1 protein fragments expressed in E.coli. | |
| Calculated MW | |
| Calculated MW: 54 kDa; Observed MW: 70 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB: 1/500-1/1000 | |
| Clonality No. | |
| 6B11 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| YAP (Yes-associated protein, YAP65) was identified based on its ability to associate with the SH3 domain of Yes. Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. | |
| Research Field | |
| Signal Transduction | |
Target Information: ( P46937 ) | |
| Name | YAP1 |
| Other Names | |
| YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65 | |
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Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team