| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ1079-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ1079-20 | 2 weeks | 20 µL | $149.00 | |||
| ABZ1079-50 | 2 weeks | 50 µL | $325.00 |
Product Overview | |
| Name | [KO] Chk2 Mouse mAb |
|---|---|
| Accession (Primary) | O96017 |
| Host Species | Mouse |
| Isotype | IgG1 |
| Immunogen | |
| Full length human recombinant protein of human CHEK2 produced in 293T cell. | |
| Species Reactivity | |
| Reacts With | Rat |
| Calculated MW | |
| Calculated MW: 61 kDa; Observed MW: 61 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB: 1/500-1/1000; IHC: 1/50-1/100; ICC: 1/100-1/200; FC: 1/50-1/100 | |
| Clonality No. | |
| 5C4 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function. | |
| Research Field | |
| Epigenetics and Nuclear Signaling | |
Target Information: ( O96017 ) | |
| Name | CHEK2 |
| Other Names | |
| CHEK2; CDS1; CHK2; RAD53; Serine/threonine-protein kinase Chk2; CHK2 checkpoint homolog; Cds1 homolog; Hucds1; hCds1; Checkpoint kinase 2 | |
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Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team