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>   Home   >   Products   >   Primary Antibodies   >   [KO] EGFR Mouse mAb   

[KO] EGFR Mouse mAb

 
Catalog #
ABZ1087
Application
WB, IHC-P
Uniprot Id
P00533
Reactivity
Rat
Isotype
IgG1
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ1087-100 2 weeks 100 µL $499.00
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ABZ1087-20 2 weeks 20 µL $149.00
ABZ1087-50 2 weeks 50 µL $325.00
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Product Overview

Name[KO] EGFR Mouse mAb
Accession (Primary)P00533
Host SpeciesMouse
IsotypeIgG1
Immunogen
Purified recombinant human EGFR protein fragments expressed in E.coli.
Species Reactivity
Reacts WithRat
Calculated MW
Calculated MW: 134 kDa; Observed MW: 175 kDa
Buffer System
Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB: 1/500-1/1000; IHC: 1/50-1/100
Clonality No.
1B10
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.
Research Field
Signal Transduction

Target Information: ( P00533 )

NameEGFR
Other Names
EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
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