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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ1091-100 | 2 weeks | 100 µL | $499.00 |
Select product before adding to cart
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| ABZ1091-20 | 2 weeks | 20 µL | $149.00 | |||
| ABZ1091-50 | 2 weeks | 50 µL | $325.00 |
Product Overview | |
| Name | [KO] ERCC1 Mouse mAb |
|---|---|
| Accession (Primary) | P07992 |
| Host Species | Mouse |
| Isotype | IgG2b |
| Immunogen | |
| Full length human recombinant protein of human ERCC1 produced in 293T cell. | |
| Species Reactivity | |
| Reacts With | Rat |
| Calculated MW | |
| Calculated MW: 33 kDa; Observed MW: 40 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB: 1/500-1/1000; IHC: 1/50-1/100; ICC: 1/100-1/200 | |
| Clonality No. | |
| 2E12 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| DNA repair systems operate in all living cells to manage a variety of DNA lesions. Nucleotide excision repair (NER) is implemented in cases where bulky helix-distorting lesions occur, such as those brought about by UV and certain chemicals. Research studies have shown that expression of ERCC1 is related to survival rate and response to chemotherapeutic drugs in several human cancers including non-small cell lung cancer (NSCLC). | |
| Research Field | |
| Epigenetics and Nuclear Signaling | |
Target Information: ( P07992 ) | |
| Name | ERCC1 |
| Other Names | |
| ERCC1; DNA excision repair protein ERCC-1 | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team
