| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ1092-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ1092-20 | 2 weeks | 20 µL | $149.00 | |||
| ABZ1092-50 | 2 weeks | 50 µL | $325.00 |
Product Overview | |
| Name | [KO] AKT1 Mouse mAb |
|---|---|
| Accession (Primary) | P31749 |
| Host Species | Mouse |
| Isotype | IgG1 |
| Immunogen | |
| Full length human recombinant protein of human AKT1 produced in 293T cell. | |
| Species Reactivity | |
| Reacts With | Rat |
| Calculated MW | |
| Calculated MW: 56 kDa; Observed MW: 60 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB: 1/500-1/1000; IHC: 1/50-1/100; FC: 1/50-1/100 | |
| Clonality No. | |
| 3B4 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Akt, also referred to as PKB or Rac, plays a critical role in controlling survival and apoptosis. This protein kinase is activated by insulin and various growth and survival factors to function in a wortmannin-sensitive pathway involving PI3 kinase. Akt is activated by phospholipid binding and activation loop phosphorylation at Thr308 by PDK1 and by phosphorylation within the carboxy terminus at Ser473. | |
| Research Field | |
| Neuroscience | |
Target Information: ( P31749 ) | |
| Name | AKT1 |
| Other Names | |
| AKT1; PKB; RAC; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team