| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ1102-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ1102-20 | 2 weeks | 20 µL | $149.00 | |||
| ABZ1102-50 | 2 weeks | 50 µL | $325.00 |
Product Overview | |
| Name | [KO] DDX58 Mouse mAb |
|---|---|
| Accession (Primary) | O95786 |
| Host Species | Mouse |
| Isotype | IgG2a |
| Immunogen | |
| Full length human recombinant protein of human DDX58 produced in 293T cell. | |
| Calculated MW | |
| Calculated MW: 107 kDa; Observed MW: 107 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB: 1/500-1/1000; IHC: 1/50-1/100 | |
| Clonality No. | |
| 6C1 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Retinoic acid inducible gene I (RIG-I) is a 925 amino acid, interferon-inducible cellular DExD/H box RNA helicase that activates type I interferon (IFN), an important effector of the innate immune system that is sensitive to these dsRNA viruses. dsRNA is normally present in very low quantities in cells, so when a virus is present, the elevated levels of dsRNA act as a sign telling RIG-I to activate the production of IFN. | |
| Research Field | |
| Epigenetics and Nuclear Signaling | |
Target Information: ( O95786 ) | |
| Name | DDX58 |
| Other Names | |
| RIG-I-like receptor 1; RLR-1; RLR1; Retinoic acid-inducible gene 1 protein; RIG-1; RIG1; RIG-I; RIGI | |
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Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team