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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ1120-100 | 2 weeks | 100 µL | $499.00 |
Select product before adding to cart
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||
| ABZ1120-20 | 2 weeks | 20 µL | $149.00 | |||
| ABZ1120-50 | 2 weeks | 50 µL | $325.00 |
Product Overview | |
| Name | [KO] APE1 Mouse mAb |
|---|---|
| Accession (Primary) | P27695 |
| Host Species | Mouse |
| Isotype | IgG2a |
| Immunogen | |
| Purified recombinant human APEX1 protein fragments expressed in E.coli. | |
| Species Reactivity | |
| Reacts With | Rat |
| Calculated MW | |
| Calculated MW: 36 kDa; Observed MW: 36 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB: 1/500-1/1000; IHC: 1/50-1/100 | |
| Clonality No. | |
| 2A4 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Ape1 initiates the repair of abasic sites and is essential for the base excision repair (BER) pathway. Repair activities of Ape1 are stimulated by interaction with XRCC1, another essential protein in BER. Ape1 functions as a redox factor that maintains transcription factors in an active, reduced state but can also function in a redox-independent manner as a transcriptional cofactor to control different cellular fates such as apoptosis, proliferation and differentiation. | |
| Research Field | |
| Epigenetics and Nuclear Signaling | |
Target Information: ( P27695 ) | |
| Name | APEX1 |
| Other Names | |
| APEX1; APE; APE1; APEX; APX; HAP1; REF1; DNA-(apurinic or apyrimidinic site) lyase; APEX nuclease; APEN; Apurinic-apyrimidinic endonuclease 1; AP endonuclease 1; APE-1; REF-1; Redox factor-1 | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
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Thank you,
ADMEbio Team
