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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ1122-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ1122-20 | 2 weeks | 20 µL | $149.00 | |||
| ABZ1122-50 | 2 weeks | 50 µL | $325.00 |
Product Overview | |
| Name | [KO] Insulin Degrading Enzyme Mouse mAb |
|---|---|
| Accession (Primary) | P14735 |
| Host Species | Mouse |
| Isotype | IgG2b |
| Immunogen | |
| Purified recombinant human IDE protein fragments expressed in E.coli. | |
| Species Reactivity | |
| Reacts With | Rat |
| Calculated MW | |
| Calculated MW: 118 kDa; Observed MW: 118 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB: 1/500-1/1000 | |
| Clonality No. | |
| 4E5 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. | |
| Research Field | |
| Neuroscience | |
Target Information: ( P14735 ) | |
| Name | IDE |
| Other Names | |
| INSULYSIN; Insulin degrading enzyme; IDE | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
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ADMEbio Team
