| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ1137-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ1137-20 | 2 weeks | 20 µL | $149.00 | |||
| ABZ1137-50 | 2 weeks | 50 µL | $325.00 |
Product Overview | |
| Name | [KO] Smad1 Mouse mAb |
|---|---|
| Accession (Primary) | Q15797 |
| Host Species | Mouse |
| Isotype | IgG1 |
| Immunogen | |
| Full length human recombinant protein of human SMAD1 produced in 293T cell. | |
| Species Reactivity | |
| Reacts With | Rat |
| Calculated MW | |
| Calculated MW: 52 kDa; Observed MW: 55 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB: 1/500-1/1000; IHC: 1/50-1/100 | |
| Clonality No. | |
| 2E2 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression. | |
| Research Field | |
| Signal Transduction | |
Target Information: ( Q15797 ) | |
| Name | SMAD1 |
| Other Names | |
| SMAD1; BSP1; MADH1; MADR1; Mothers against decapentaplegic homolog 1; MAD homolog 1; Mothers against DPP homolog 1; JV4-1; Mad-related protein 1; SMAD family member 1; SMAD 1; Smad1; hSMAD1; Transforming growth factor-beta-signaling protein | |
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ADMEbio Team
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ADMEbio Team