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>   Home   >   Products   >   Primary Antibodies   >   [KO] PIK3C2A Mouse mAb   

[KO] PIK3C2A Mouse mAb

 
Catalog #
ABZ1151
Application
WB, IHC-P
Uniprot Id
O00443
Reactivity
Rat
Isotype
IgG2a
 
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 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ1151-100 2 weeks 100 µL $499.00
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ABZ1151-20 2 weeks 20 µL $149.00
ABZ1151-50 2 weeks 50 µL $325.00
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Product Overview

Name[KO] PIK3C2A Mouse mAb
Accession (Primary)O00443
Host SpeciesMouse
IsotypeIgG2a
Immunogen
Purified recombinant human PIK3C2A protein fragments expressed in E.coli.
Species Reactivity
Reacts WithRat
Calculated MW
Calculated MW: 191 kDa; Observed MW: 191 kDa
Buffer System
Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB: 1/500-1/1000; IHC: 1/50-1/100
Clonality No.
3D9
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008]
Research Field
Signal Transduction

Target Information: ( O00443 )

NamePIK3C2A
Other Names
CPK; PI3-K-C2(ALPHA); PI3-K-C2A; PI3K-C2-alpha; PI3K-C2alpha
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