| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ1151-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ1151-20 | 2 weeks | 20 µL | $149.00 | |||
| ABZ1151-50 | 2 weeks | 50 µL | $325.00 |
Product Overview | |
| Name | [KO] PIK3C2A Mouse mAb |
|---|---|
| Accession (Primary) | O00443 |
| Host Species | Mouse |
| Isotype | IgG2a |
| Immunogen | |
| Purified recombinant human PIK3C2A protein fragments expressed in E.coli. | |
| Species Reactivity | |
| Reacts With | Rat |
| Calculated MW | |
| Calculated MW: 191 kDa; Observed MW: 191 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB: 1/500-1/1000; IHC: 1/50-1/100 | |
| Clonality No. | |
| 3D9 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008] | |
| Research Field | |
| Signal Transduction | |
Target Information: ( O00443 ) | |
| Name | PIK3C2A |
| Other Names | |
| CPK; PI3-K-C2(ALPHA); PI3-K-C2A; PI3K-C2-alpha; PI3K-C2alpha | |
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Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team