| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ1160-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ1160-20 | 2 weeks | 20 µL | $149.00 | |||
| ABZ1160-50 | 2 weeks | 50 µL | $325.00 |
Product Overview | |
| Name | [KO] ERK5 Mouse mAb |
|---|---|
| Accession (Primary) | Q13164 |
| Host Species | Mouse |
| Isotype | IgG2a |
| Immunogen | |
| Full length human recombinant protein of human MAPK7 produced in 293T cell. | |
| Species Reactivity | |
| Reacts With | Rat |
| Calculated MW | |
| Calculated MW: 88 kDa; Observed MW: 110 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB: 1/500-1/1000 | |
| Clonality No. | |
| 3D4 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Erk5 (Mitogen-activated protein kinase 7, Big mitogen-activated protein kinase 1) is a member of the MAPK superfamily implicated in the regulation numerous cellular processes including proliferation, differentiation, and survival. In neuronal cells, Erk5 is required for NGF-induced neurite outgrowth, neuronal homeostasis, and survival. Erk5 is thought to play a role in blood vessel integrity via maintenance of endothelial cell migration and barrier function. | |
| Research Field | |
| Neuroscience | |
Target Information: ( Q13164 ) | |
| Name | MAPK7 |
| Other Names | |
| Big MAP kinase 1; BMK 1; BMK 1 kinase; BMK-1; BMK1; BMK1 Kinase; ERK 4; ERK 5; ERK-5; ERK4; ERK5; MAP kinase 7; MAPK 7; Mitogen Activated Protein Kinase | |
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Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team