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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ1166-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ1166-20 | 2 weeks | 20 µL | $149.00 | |||
| ABZ1166-50 | 2 weeks | 50 µL | $325.00 |
Product Overview | |
| Name | [KO] OTUD7B Mouse mAb |
|---|---|
| Accession (Primary) | Q6GQQ9 |
| Host Species | Mouse |
| Isotype | IgG1 |
| Immunogen | |
| Purified recombinant human OTUD7B protein fragments expressed in E.coli. | |
| Species Reactivity | |
| Reacts With | Rat |
| Calculated MW | |
| Calculated MW: 93 kDa; Observed MW: 93 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB: 1/500-1/1000 | |
| Clonality No. | |
| 2E2 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Negative regulator of the non-canonical NF-kappa-B pathway that acts by mediating deubiquitination of TRAF3, an inhibitor of the NF-kappa-B pathway, thereby acting as a negative regulator of B-cell responses. In response to non-canonical NF-kappa-B stimuli, deubiquitinates 'Lys-48'-linked polyubiquitin chains of TRAF3, preventing TRAF3 proteolysis and over-activation of non-canonical NF-kappa-B. Negatively regulates mucosal immunity against infections (By similarity). | |
| Research Field | |
| Cell Biology | |
Target Information: ( Q6GQQ9 ) | |
| Name | OTUD7B |
| Other Names | |
| CEZANNE; ZA20D1 | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
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ADMEbio Team
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ADMEbio Team
