| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ1178-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ1178-20 | 2 weeks | 20 µL | $149.00 | |||
| ABZ1178-50 | 2 weeks | 50 µL | $325.00 |
Product Overview | |
| Name | [KO] ATG3 Mouse mAb |
|---|---|
| Accession (Primary) | Q9NT62 |
| Host Species | Mouse |
| Isotype | IgG1 |
| Immunogen | |
| Full length human recombinant protein of human ATG3 produced in 293T cell. | |
| Species Reactivity | |
| Reacts With | Rat |
| Calculated MW | |
| Calculated MW: 36 kDa; Observed MW: 42 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB: 1/500-1/1000; IHC: 1/50-1/100 | |
| Clonality No. | |
| 4F6 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| E2-like enzyme involved in autophagy and mitochondrial homeostasis. Catalyzes the conjugation of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A) to phosphatidylethanolamine (PE). Catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3. | |
| Research Field | |
| Cell Biology | |
Target Information: ( Q9NT62 ) | |
| Name | ATG3 |
| Other Names | |
| APG3; APG3L; PC3-96; APG3-LIKE | |
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ADMEbio Team
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ADMEbio Team