| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ1180-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ1180-20 | 2 weeks | 20 µL | $149.00 | |||
| ABZ1180-50 | 2 weeks | 50 µL | $325.00 |
Product Overview | |
| Name | [KO] Fascin Mouse mAb |
|---|---|
| Accession (Primary) | Q16658 |
| Host Species | Mouse |
| Isotype | IgG2a |
| Immunogen | |
| Full length human recombinant protein of human FSCN1 produced in 293T cell. | |
| Species Reactivity | |
| Reacts With | Rat |
| Calculated MW | |
| Calculated MW: 55 kDa; Observed MW: 55 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB: 1/500-1/1000; IHC: 1/50-1/100 | |
| Clonality No. | |
| 3D2 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Promotes cross-linkage of parallel actin filaments during the formation of cell protrusions (lamellipodia and filopodia), and therefore plays an important role in regulating cell migration. It has been reported that fascin may also regulate filopodia formation by a mechanism independent of its actin-bundling functions, though less is known about this mechanism of action. | |
| Research Field | |
| Cell Biology | |
Target Information: ( Q16658 ) | |
| Name | FSCN1 |
| Other Names | |
| 55 kDa actin bundling protein; Actin bundling protein; FAN1; Fascin 1; Fascin; Singed (Drosophila) like (sea urchin fascin homolog like); Fascin homolog 1; Fascin | |
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ADMEbio Team
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