Hello, Sign in
My Account
My Account
New customer? Start here
| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ1190-100 | 2 weeks | 100 µL | $499.00 |
Select product before adding to cart
|
||
| ABZ1190-20 | 2 weeks | 20 µL | $149.00 | |||
| ABZ1190-50 | 2 weeks | 50 µL | $325.00 |
Product Overview | |
| Name | [KO] TDG Mouse mAb |
|---|---|
| Accession (Primary) | Q13569 |
| Host Species | Mouse |
| Isotype | IgG1 |
| Immunogen | |
| Purified recombinant human TDG protein fragments expressed in E.coli. | |
| Species Reactivity | |
| Reacts With | Rat |
| Calculated MW | |
| Calculated MW: 46 kDa; Observed MW: 55 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB: 1/500-1/1000; IHC: 1/50-1/100 | |
| Clonality No. | |
| 3C11 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq, Jul 2008] | |
| Research Field | |
| Epigenetics and Nuclear Signaling | |
Target Information: ( Q13569 ) | |
| Name | TDG |
| Other Names | |
| hTDG | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
ADMEbio welcomes feedback from our customers.
Thank you,
ADMEbio Team
