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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ1192-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ1192-20 | 2 weeks | 20 µL | $149.00 | |||
| ABZ1192-50 | 2 weeks | 50 µL | $325.00 |
Product Overview | |
| Name | [KO] TSN Mouse mAb |
|---|---|
| Accession (Primary) | Q15631 |
| Host Species | Mouse |
| Isotype | IgG1 |
| Immunogen | |
| Purified recombinant human TSN protein fragments expressed in E.coli. | |
| Species Reactivity | |
| Reacts With | Rat |
| Calculated MW | |
| Calculated MW: 26 kDa; Observed MW: 26 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB: 1/500-1/1000 | |
| Clonality No. | |
| 4C6 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. This protein encoded by this gene, when complexed with translin-associated protein X, also forms a Mg ion-dependent endoribonuclease that promotes RNA-induced silencing complex (RISC) activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012] | |
| Research Field | |
| Epigenetics and Nuclear Signaling | |
Target Information: ( Q15631 ) | |
| Name | TSN |
| Other Names | |
| BCLF-1; C3PO; RCHF1; REHF-1; TBRBP; TRSLN | |
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ADMEbio Team
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ADMEbio Team
