| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ1210-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ1210-20 | 2 weeks | 20 µL | $149.00 | |||
| ABZ1210-50 | 2 weeks | 50 µL | $325.00 |
Product Overview | |
| Name | [KO] SQSTM1/p62 Mouse mAb |
|---|---|
| Accession (Primary) | Q13501 |
| Host Species | Mouse |
| Isotype | IgG2b |
| Immunogen | |
| Full length human recombinant protein of human SQSTM1 produced in 293T cell. | |
| Species Reactivity | |
| Reacts With | Rat |
| Calculated MW | |
| Calculated MW: 48 kDa; Observed MW: 65 kDa | |
| Buffer System | |
| Liquid in PBS containing 50% glycerol, 1% BSA and 0.02% sodium azide, pH 7.3. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB: 1/500-1/1000; IHC: 1/50-1/100; FC: 1/50-1/100 | |
| Clonality No. | |
| 1F2 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. | |
| Research Field | |
| Signal Transduction | |
Target Information: ( Q13501 ) | |
| Name | SQSTM1 |
| Other Names | |
| p60; p62; A170; DMRV; OSIL; PDB3; ZIP3; p62B; NADGP; FTDALS3 | |
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Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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ADMEbio Team
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ADMEbio Team