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VPS4A Rabbit mAb

 
Catalog #
ABZ1753
Application
WB, IF, ICC, IHC-P
Uniprot Id
Q9UN37
Reactivity
Human, Mouse, Rat
Isotype
IgG
 
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  • Western blot analysis of VPS4a in K562, rat Brain, C6, 3T3 lysates using VPS4A antibody.
  • Immunocytochemistry analysis of VPS4a(green) in Hela using VPS4a antibody,and DAPI(blue)
  • Immunohistochemistry analysis of paraffin-embedded Human breast cancer using VPS4a antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ1753-100 2 weeks 100 µL $499.00
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ABZ1753-20 2 weeks 20 µL $149.00
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Product Overview

NameVPS4A Rabbit mAb
Accession (Primary)Q9UN37
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman, Mouse, Rat
Calculated MW
Calculated MW: 49 kDa; Observed MW: 49 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000; IHC-P-1:500-1:2000; ICC/IF-1:50-1:100
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16; the gene for the other resides on chromosome 18.

Target Information: ( Q9UN37 )

NameVPS4A
Gene ID27183
Other Names
vacuolar protein sorting 4 homolog A; SKD1; SKD2; VPS4; SKD1A; VPS4-1
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