| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ2032-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ2032-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | Adiponectin Rabbit mAb |
|---|---|
| Accession (Primary) | Q60994 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Mouse, Rat |
| Calculated MW | |
| Calculated MW: 27 kDa; Observed MW: 30 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:500-1:1000; IHC-P-1:500-1:2000; ICC/IF-1:500-1:1000; FC-1:20-1:50 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW. | |
Target Information: ( Q60994 ) | |
| Name | Adipoq |
| Gene ID | 11450 |
| Other Names | |
| Ad; APN; Acdc; Adid; apM1; 30kDa; GBP28; adipo; Acrp30 | |
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ADMEbio Team
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ADMEbio Team