| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ2077-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ2077-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | ADRM1/ARM-1 Rabbit mAb |
|---|---|
| Accession (Primary) | Q16186 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Human |
| Calculated MW | |
| Calculated MW: 42 kDa; Observed MW: 42 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:5000; IHC-P-1:50-1:100; ICC/IF-1:500-1:1000; FC-1:50-1:100; IP-1:10-1:100 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| Proteasomal ubiquitin receptor ADRM1 is a protein that is encoded by the ADRM1 gene. It is a component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. ADRM1 engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation. | |
Target Information: ( Q16186 ) | |
| Name | ADRM1 |
| Gene ID | 11047 |
| Other Names | |
| ARM1; ARM-1; GP110; 110 kDa cell membrane glycoprotein; adhesion regulating molecule 1; Adhesion-regulating molecule 1; | |
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