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ADRM1/ARM-1 Rabbit mAb

 
Catalog #
ABZ2077
Application
WB, IF, FC, IP, ICC, IHC-F, IHC-P
Uniprot Id
Q16186
Reactivity
Human
Isotype
IgG
 
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  • Western blot analysis of ADRM1 in K562, Hela lysates using ADRM1 antibody.
  • Immunocytochemistry analysis of ADRM1(green) in Hela using ADRM1 antibody,and DAPI(blue)
  • Immunohistochemistry analysis of paraffin-embedded Human breast cancer using ADRM1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
 Catalog #AvailabilitySizeQuantityUnit Price Save For Later Wish List
ABZ2077-100 2 weeks 100 µL $499.00
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ABZ2077-20 2 weeks 20 µL $149.00
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Product Overview

NameADRM1/ARM-1 Rabbit mAb
Accession (Primary)Q16186
Host SpeciesRabbit
ClonalityMonoclonal
IsotypeIgG
Species Reactivity
Reacts WithHuman
Calculated MW
Calculated MW: 42 kDa; Observed MW: 42 kDa
Buffer System
Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Recommended Dilution
WB-1:1000-1:5000; IHC-P-1:50-1:100; ICC/IF-1:500-1:1000; FC-1:50-1:100; IP-1:10-1:100
Purification
Affinity Purified
Conjugation
Unconjugated
Modification
Unmodified
Form
Liquid
Background
Proteasomal ubiquitin receptor ADRM1 is a protein that is encoded by the ADRM1 gene. It is a component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. ADRM1 engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation.

Target Information: ( Q16186 )

NameADRM1
Gene ID11047
Other Names
ARM1; ARM-1; GP110; 110 kDa cell membrane glycoprotein; adhesion regulating molecule 1; Adhesion-regulating molecule 1;
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