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| Catalog # | Availability | Size | Quantity | Unit Price | Save For Later Wish List | |
|---|---|---|---|---|---|---|
| ABZ2109-100 | 2 weeks | 100 µL | $499.00 |
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| ABZ2109-20 | 2 weeks | 20 µL | $149.00 |
Product Overview | |
| Name | RAGE Rabbit mAb |
|---|---|
| Accession (Primary) | Q15109 |
| Host Species | Rabbit |
| Clonality | Monoclonal |
| Isotype | IgG |
| Species Reactivity | |
| Reacts With | Mouse, Rat |
| Calculated MW | |
| Calculated MW: 43 kDa; Observed MW: 55 kDa | |
| Buffer System | |
| Liquid in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. | |
| Storage | |
| Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | |
| Recommended Dilution | |
| WB-1:1000-1:5000 | |
| Purification | |
| Affinity Purified | |
| Conjugation | |
| Unconjugated | |
| Modification | |
| Unmodified | |
| Form | |
| Liquid | |
| Background | |
| The receptor for advanced glycation end products (RAGE) is member of the immunoglobulin (Ig) superfamily. Mediates interactions of advanced glycosylation end products (AGE). Binding of AGEs to RAGE results in the induction of cellular oxidant stress and activation of the transcription factor NFkB. Evidence suggests that the induction of oxidant stress results in the activation of an intracellular cascade involving p21 ras and MAP kinase, which leads to activation of transcription. | |
Target Information: ( Q15109 ) | |
| Name | AGER |
| Gene ID | 177 |
| Other Names | |
| AGER; RAGE; Advanced glycosylation end product-specific receptor; Receptor for advanced glycosylation end products | |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from ADMEbio to advance their research.
Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
Thank you,
ADMEbio Team
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ADMEbio Team
